A Novel Conditional Adra2a-Knockout Mouse Line Reveals Cell-specific Contributions to Specific Dimensions of Sedation
Noah L Fryou, Timothy Jiang, Nathan Frick, Paula Kwasniewska, Mikhail Y. Lipin, Max B. Kelz, STEVEN A. THOMAS, Andrew R. McKinstry-Wu
This study creates a conditional Adra2a knockout mouse line and shows cell-specific contributions of the 2A adrenergic receptor to sedation, hypnosis, and hypothermia.
bioRxiv · Apr 17, 2026 · PreprintNeuroscience