p300 Is an Obligate Integrator of Combinatorial Transcription Factor Inputs
J. J. Ferrie, J. P. Karr, T. G. Graham, G. M. Dailey, G. Zhang, R. Tjian, X. Darzacq
This study shows p300 requires multiple transcription factor interaction domains for chromatin binding and catalytic regulation, highlighting the necessity of combinatorial TF inputs for coactivator function.
bioRxiv · May 18, 2023Biophysics