Author

T. H. Benedyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. E. Deane· 3 shared S. C. Graham· 3 shared C. M. Crump· 2 shared C. M. Jeffries· 2 shared D. I. Svergun· 2 shared M. Shamin· 2 shared V. Connor· 2 shared A. E. Firth· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

J. E. Deane

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Herpes simplex virus 1 protein pUL21 stimulates cellular ceramide transport by activating CERT

T. H. Benedyk, V. Connor, E. R. Caroe, M. Shamin, D. I. Svergun, J. E. Deane, C. M. Jeffries, C. M. Crump, S. C. Graham

This paper shows HSV-1 protein pUL21 activates CERT to increase ceramide to sphingomyelin conversion, but does not affect virus replication or spread.

bioRxiv · Jun 1, 2022Microbiology

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

T. H. Benedyk, J. Muenzner, V. Connor, Y. Han, K. Brown, K. J. Wijesinghe, Y. Zhuang, S. Colaco, G. A. Stoll, O. S. Tutt, S. Svobodova, D. I. Svergun, N. A. Bryant, J. E. Deane, A. E. Firth, , S. C. Graham

This study identifies pUL21 as a viral phosphatase adaptor that promotes HSV-1 replication and spread by directing dephosphorylation and antagonizing pUS3 kinase activity.

bioRxiv · Apr 13, 2021Microbiology

The lipid transfer protein Saposin B does not directly bind CD1d for lipid antigen loading

M. Shamin, T. H. Benedyk, S. C. Graham, J. E. Deane

This study investigates whether Saposin B directly binds CD1d for lipid antigen loading and finds no direct interaction.

bioRxiv · Jul 11, 2019Biochemistry