Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis
J. J. Li, N. Xin, C. Yang, L. A. Tavizon, R. Hong, J. Park, T. I. Moore, R. G. Tharyan, A. Antebi, H.-E. Kim
The paper identifies a Mitochondria to ER Stress Response (MERSR) that enhances proteostasis by modulating UPRER and PERK-eIF2 signaling in disease models.
bioRxiv · Sep 7, 2023Cell Biology