Conditional Requirement for Dimerization of the Membrane-Binding Module of BTK
T. J. Eisen, S. Ghaffari-Kashani, J. T. Groves, A. Weiss, J. Kuriyan
This study investigates whether BTK dimerization via its PH-TH module is required for signaling in B and T cells, finding it is not necessary in B cells but essential in T cells.
bioRxiv · Oct 5, 2023 · PreprintBiochemistry