Author

T. M. Mascenik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. E. Lee· 3 shared S. H. Randell· 3 shared C. A. Lewis· 2 shared A. J. Kimple· 1 shared A. Schäfer· 1 shared C. E. Edwards· 1 shared C. Ehre· 1 shared H. Dang· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

R. E. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Viral Airway Injury Promotes Cell Engraftment in an In Vitro Model of Cystic Fibrosis Cell Therapy

R. E. Lee, T. M. Mascenik, S. C. Major, C. A. Lewis, J. E. Bear, R. J. Pickles, S. H. Randell

This study shows that viral airway injury enhances cell engraftment in an in vitro CF model by creating conditions that favor non-CF cell integration and functional CFTR recovery.

bioRxiv · Nov 14, 2022 · PreprintCell Biology

Robust W1282X-CFTR rescue by a small molecule GSPT1 degrader

R. E. Lee, C. A. Lewis, L. He, S. C. Gallant, T. M. Mascenik, H. Dang, L. C. Morton, J. T. Minges, J. W. Theile, N. A. Castle, M. R. Knowles, A. J. Kimple, S. H. Randell

The paper develops Bmi-1/hTERT cell lines to model CFTR variants and shows that CC-90009 partially rescues W1282X-CFTR function while affecting sodium channel activity.

bioRxiv · Sep 28, 2021 · PreprintPathology

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

Y. J. Hou, S. Chiba, P. Halfmann, C. Ehre, M. Kuroda, K. H. Dinnon, S. R. Leist, A. Schäfer, N. Nakajima, K. Takahashi, R. E. Lee, T. M. Mascenik, C. E. Edwards, L. V. Tse, R. C. Boucher, , R. S. Baric

This study shows the SARS-CoV-2 D614G variant replicates more efficiently and transmits faster in hamsters than the wildtype virus.

bioRxiv · Sep 28, 2020Microbiology