Author

T. McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Ecology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Chowdhury· 1 shared A. Dona· 1 shared A. Dwyer· 1 shared A. Krishnan· 1 shared A. Owen· 1 shared A. Savage· 1 shared A. Schorg· 1 shared A. Valentijn· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Chowdhury

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SARS-CoV-2 Vaccine Booster Elicits Robust Prolonged Maternal Antibody Responses and Passive Transfer Via The Placenta And Breastmilk

N. E. Marshall, M. B. Blanton, B. M. Doratt, D. C. Malherbe, M. Rincon, H. True, T. McDonald, C. Beauregard, R. Adatorwovor, I. Messaoudi

This study evaluates maternal SARS-CoV-2 vaccine antibody responses in circulation and breastmilk, showing that boosters increase antibody levels for passive transfer to newborns.

bioRxiv · Nov 29, 2022 · PreprintImmunology

Single Particle Tracking With Compressive Sensing Using Progressive Refinement Method On Sparse Recovery (spt-PRIS)

X. Yi, R. Shrestha, T. McDonald, D. Chen, H. Bhatia, V. Pascucci, T. Turbyville, P.-T. Bremer

This study introduces spt-PRIS, a new single particle tracking method that improves localization in high-density datasets with overlapping PSFs, showing effectiveness for KRAS4b subpopulation analysis.

bioRxiv · May 13, 2022 · PreprintBiophysics

Optimisation and validation of a sensitive bioanalytical method for niclosamide.

U. Arshad, H. Pertinez, H. Box, L. Tatham, R. Rajoli, M. Neary, J. Sharp, A. Valentijn, J. Hobson, C. Unsworth, A. Dwyer, A. Savage, T. McDonald, S. Rannard, P. Curley, A. Owen

The paper develops and validates a sensitive LC-MS/MS assay for niclosamide to study its pharmacokinetics and potential use in preclinical and clinical evaluations.

bioRxiv · Jan 13, 2021 · PreprintPharmacology & Toxicology

Evidence of Absence Regression: A Binomial N-Mixture Model for Estimating Fatalities at Wind Power Facilities

T. McDonald, K. Bay, J. Studyvin, J. Leckband, A. Schorg, J. McIvor

The paper introduces a binomial N-mixture model to estimate bird and bat fatalities at wind power facilities using sparse carcass count data.

bioRxiv · Jan 21, 2020Ecology

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

D. Viola, A. Dona, E. Caserta, E. Troadec, E. G. Gunes, F. Besi, T. McDonald, L. Ghoda, J. F. Sanchez, J. Khalife, M. Martella, C. Karanes, M. Htut, X. Wang, M. Rosenzweig, , F. Pichiorri

This study shows that daratumumab targets CD38+ NK cells to induce immune activation and anti-myeloma activity despite reducing total NK cell frequency.

bioRxiv · Nov 22, 2019Cancer Biology