Author

T. Srivastava

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

E. Derbyshire· 2 shared J. Chongtham· 2 shared A. A. Seethy· 1 shared A. Mohan· 1 shared A. Y. Sinha· 1 shared B. M. Discher· 1 shared C. F. A. Pasaje· 1 shared C. Hernandez-Chavez· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersMicrobiology

E. Derbyshire

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Huntingtin Interacting Protein-1 expression is regulated via HIF2 axis in Lung Adenocarcinoma

P. Prasad, J. Chongtham, S. C. Tripathi, N. K. Ganguly, S. A. Mittal, T. Srivastava

The paper investigates HIP1 expression regulation via the HIF2 axis in lung adenocarcinoma, showing its role in tumor suppression and metabolic changes.

bioRxiv · Mar 27, 2023 · PreprintCancer Biology

The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

P. M. Exconde, C. Hernandez-Chavez, M. B. Bray, J. L. Lopez, T. Srivastava, M. S. Egan, J. Zhang, S. Shin, B. M. Discher, C. Y. Taabazuing

This study identifies that the tetrapeptide sequence of IL-1β regulates its cleavage by non-canonical inflammasomes, revealing a mechanism for inflammation control.

bioRxiv · Feb 16, 2023 · PreprintImmunology

Interaction of hypoxia and nicotine acetylcholine receptor signaling network reveals a novel mechanism for lung adenocarcinoma progression in never-smokers

T. Srivastava, N. Pandey, J. Chongtham, S. Pal, A. Mohan

The paper investigates the interaction between hypoxia and nicotine acetylcholine receptor signaling in lung adenocarcinoma, finding that hypoxia increases nAChR-7 levels and stabilizes HIF-1 through a feedback loop, contributing to disease progression in never-smokers.

bioRxiv · Sep 8, 2021 · PreprintCancer Biology

Genotypic and antigenic study of SARS-CoV-2 from an Indian isolate.

R. Dhar, A. Y. Sinha, A. A. Seethy, S. A. Matta, K. Pethusamy, T. Srivastava, S. Singh, I. Mukherjee, S. Sarkar, R. Minocha, K. Purkayastha, J. B. Sharma, S. Paine, S. Karmakar

The paper analyzes the genotypic and antigenic characteristics of an Indian SARS-CoV-2 isolate, identifying its strain and predicting B and T cell epitopes for vaccine design.

bioRxiv · Jun 10, 2020 · PreprintBiochemistry

Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

K.-Y. Lu, C. F. A. Pasaje, T. Srivastava, D. R. Loiselle, J. Niles, E. Derbyshire

This study identifies PI(3)P and PfHsp70-1 as factors protecting Plasmodium falciparum from heat-induced cell death by stabilizing the digestive vacuole.

bioRxiv · Mar 17, 2020Microbiology

RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection

M. Toro-Moreno, K. Sylvester, T. Srivastava, D. Posfai, E. Derbyshire

This paper uses RNA-seq to analyze the early transcriptome of Plasmodium berghei liver infection, identifying differentially expressed genes and transcription factor targets.

mBio · Feb 25, 2020Peer-reviewedMicrobiology