Author

T. Yanagihara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

I. Okamoto· 2 shared K. Ask· 2 shared K. Hata· 2 shared K. Kunimura· 2 shared K. Matsubara· 2 shared K. Suzuki· 2 shared K. Tsubouchi· 2 shared S. Ikegame· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

I. Okamoto

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Exploratory mass cytometry analysis reveals immunophenotypes of cancer treatment-related pneumonitis

T. Yanagihara, K. Hata, K. Matsubara, K. Kunimura, K. Suzuki, K. Tsubouchi, S. Ikegame, Y. Baba, Y. Fukui, I. Okamoto

The paper uses mass cytometry to analyze immune cell subsets in bronchoalveolar lavage fluid from patients with PCP, DI-ILD, and ICI-ILD, revealing distinct immunophenotypes associated with each condition.

bioRxiv · Feb 21, 2023Immunology

Mass cytometry identifies characteristic immune cell subsets in bronchoalveolar lavage fluid from interstitial lung diseases

K. Hata, T. Yanagihara, K. Matsubara, K. Kunimura, K. Suzuki, K. Tsubouchi, D. Eto, H. Ando, M. Uehara, S. Ikegame, Y. Baba, Y. Fukui, I. Okamoto

The paper uses mass cytometry to identify distinct immune cell subsets in BALF from ILD patients, revealing disease-specific immune signatures.

bioRxiv · Jan 12, 2023Immunology

Connective-Tissue Growth Factor (CTGF/CCN2) Contributes to TGF-β1-Induced Lung Fibrosis

T. Yanagihara, S. G. Chong, M. Gholiof, K. E. Lipson, Q. Zhou, C. Scallan, C. Upagupta, J. Tikkanen, S. Keshavjee, K. Ask, M. R. Kolb

This study shows CTGF contributes to TGF-β1-induced lung fibrosis in a rat model and patients with IPF, and that pamrevlumab can partially reduce fibrosis.

bioRxiv · Jul 4, 2020 · PreprintCell Biology

Expression of the endocannabinoid system in the human airway epithelial cells: Impact of sex and chronic respiratory disease status

M. F. Fantauzzi, J. A. Aguiar, B. J.-M. Tremblay, T. Yanagihara, A. Chandiramohan, S. Revill, M. H. Ryu, C. Carlsten, K. Ask, M. Stampfli, A. C. Doxey, J. A. Hirota

The paper analyzes gene expression of the endocannabinoid system in human airway epithelial cells, showing differential expression by disease status and minimal sex impact.

bioRxiv · Mar 1, 2020Cell Biology

Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice

H. Mikumo, T. Yanagihara, N. Hamada, E. Harada, S. O. Suetsugu, C. I. Harada, M. A. Omori, K. Suziki, T. Yokoyama, Y. Nakanishi

This study shows that sivelestat reduces gefitinib-induced pneumonitis in mice by lowering neutrophil elastase activity and improving survival.

bioRxiv · Feb 14, 2017Pharmacology & Toxicology