Author

J. A. Aguiar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Doxey· 4 shared J. A. Hirota· 4 shared K. Ask· 4 shared S. Revill· 4 shared B. J.-M. Tremblay· 3 shared N. Tiessen· 3 shared A. Chandiramohan· 2 shared C. Carlsten· 2 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersImmunology

A. C. Doxey

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Author profile →

4 papers

Recent·Most cited

Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP

Y. Kim, V. Hou, R. D. Huff, J. A. Aguiar, S. Revill, N. Tiessen, C. Cao, M. S. Miller, M. D. Inman, K. Ask, A. C. Doxey, J. A. Hirota

This study shows that inhibiting PDE4 or ABCC4 enhances the anti-inflammatory effects of LABA/GCS in human airway epithelial cells exposed to viral stimuli.

bioRxiv · Nov 9, 2020Immunology

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

J. A. Aguiar, B. J.-M. Tremblay, M. J. Mansfield, O. Woody, B. Lobb, A. Banerjee, A. Chandiramohan, N. Tiessen, A. Dvorkin-Gheva, S. Revill, M. S. Miller, C. Carlsten, L. Organ, C. Joseph, A. John, , J. A. Hirota

The paper examines gene expression and protein localization of potential SARS-CoV-2 receptors in human airway epithelial cells and lung tissue, finding low ACE2 expression and confirming other candidate receptors.

bioRxiv · Apr 7, 2020Immunology

Expression of the endocannabinoid system in the human airway epithelial cells: Impact of sex and chronic respiratory disease status

M. F. Fantauzzi, J. A. Aguiar, B. J.-M. Tremblay, T. Yanagihara, A. Chandiramohan, S. Revill, M. H. Ryu, C. Carlsten, K. Ask, M. Stampfli, A. C. Doxey, J. A. Hirota

The paper analyzes gene expression of the endocannabinoid system in human airway epithelial cells, showing differential expression by disease status and minimal sex impact.

bioRxiv · Mar 1, 2020Cell Biology

ABCF1 regulates dsDNA-induced immune responses in human airway epithelial cells

Q. T. Cao, J. A. Aguiar, B. J.-M. Tremblay, N. Abbas, N. Tiessen, S. Revill, N. Makhdami, A. Ayoub, G. Cox, K. Ask, A. C. Doxey, J. A. Hirota

This study identifies ABCF1 as a cytosolic nucleic acid sensor in human airway epithelial cells that modulates antiviral responses and interacts with TLR signaling.

bioRxiv · Feb 8, 2020Immunology