Author

T.-C. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. A. MacDuff· 2 shared K. Iwai· 2 shared M. J. Wood· 2 shared V. L. Hartley· 2 shared A. M. Qaqish· 1 shared B. T. Studnicka· 1 shared C.-C. Wu· 1 shared C.-J. Hsu· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

D. A. MacDuff

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Author profile →

3 papers

Recent·Most cited

HOIL1 regulates group 3 innate lymphoid cell numbers in the colon and protects against systemic dissemination, colonic ulceration, and lethality from Citrobacter rodentium infection

V. L. Hartley, A. M. Qaqish, M. J. Wood, B. T. Studnicka, K. Iwai, T.-C. Liu, D. A. MacDuff

This study shows HOIL1 is critical for limiting C. rodentium infection by regulating ILC3 numbers and inflammatory responses in mice.

bioRxiv · May 22, 2023Immunology

Computer simulations reveal pathogenicity and inheritance modes of hearing loss-causing germinal variants

C.-Y. Tsai, Y.-C. Lu, Y.-H. Chan, Y.-Y. Chang, S.-W. Lin, T.-C. Liu, C.-J. Hsu, P.-L. Chen, L.-W. Yang, C.-C. Wu

The paper uses molecular dynamics simulations to show how GJB2 variants cause hearing loss by altering ion channel function and demonstrates a recessive inheritance pattern in mice.

bioRxiv · May 2, 2022 · PreprintBiophysics

HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine

M. J. Wood, J. N. Marshall, V. L. Hartley, T.-C. Liu, K. Iwai, T. S. Stappenbeck, D. A. MacDuff

This study shows HOIL1 deficiency in mice causes type 2 inflammation in the small intestine, characterized by increased ILC2 cells and cytokine expression, independent of IL4R signaling.

bioRxiv · Mar 9, 2022Immunology