Author

T.-F. Hsieh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Plant Biology· 6 Microbiology· 1

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Research Focus:chromatin & epigenetic regulation· 6 Organism:Arabidopsis· 5 Assay:DNA methylation· 5 Approach:experimental assay· 4 Approach:statistical model· 3 Approach:comparative / phylogenetic analysis· 2 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

J. M. Frost· 3 shared R. L. Fischer· 3 shared C. Zhang· 2 shared D. Zhang· 2 shared J. H. Huh· 2 shared P.-H. Hsieh· 2 shared W. Xiao· 2 shared X.-Q. Zhang· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPlant Biology

J. M. Frost

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Author profile →

7 papers

Recent·Most cited

Temporal Transcriptome Analysis Uncovers Regulatory Modules Programming Embryo Development from Embryonic Morphogenesis to Post-Germination

Y.-C. Wang, W.-H. Hsieh, C.-J. Huang, Y.-T. Jhan, J. Zhan, C.-C. Chang, T.-F. Hsieh, J.-Y. Lin

The paper profiles soybean seed embryo transcriptomes across development to identify gene functions and regulatory networks involved in reserve accumulation and germination.

bioRxiv · Dec 26, 2023 · PreprintPlant Biology

Embryo-specific epigenetic mechanisms reconstitute the CHH methylation landscape during Arabidopsis embryogenesis

P.-H. Hsieh, J. M. Frost, Y. Choi, T.-F. Hsieh, D. Zilberman, R. L. Fischer

This study identifies embryo-specific epigenetic mechanisms that reprogram CHH methylation during Arabidopsis embryogenesis, revealing distinct roles for RdDM and CMT2 pathways.

bioRxiv · Apr 6, 2023 · PreprintPlant Biology

H2A.X mutants exhibit enhanced DNA demethylation in Arabidopsis thaliana

J. M. Frost, J. Lee, P.-H. Hsieh, S. J. Lin, Y. Min, M. Bauer, A. Runkel, H.-T. Cho, T.-F. Hsieh, Y. Choi, R. L. Fischer

This study shows that H2A.X mutants in Arabidopsis thaliana exhibit reduced CG DNA methylation in endosperm, primarily in transposons and intergenic regions, suggesting H2A.X's role in maintaining methylation homeostasis.

bioRxiv · Jan 8, 2023 · PreprintPlant Biology

Loss of Linker Histone H1 in the Maternal Genome Influences DEMETER-Mediated Demethylation and Affects the Endosperm DNA Methylation Landscape

T.-F. Hsieh, Q. Han, Y.-H. Hung, C. Zhang, A. Bartels, M. Rea, H. Yang, C. Park, X.-Q. Zhang, R. L. Fsicher, W. Xiao

This study shows that loss of maternal linker histone H1 in Arabidopsis facilitates DME-mediated demethylation in heterochromatin but has limited effects on endosperm gene transcription and imprinting.

bioRxiv · Oct 17, 2022Plant Biology

A merger between compatible but divergent genomes supports allopolyploidization in the Brassicaceae family

H. Shin, J. E. Park, H. R. Park, W. L. Choi, S. H. Yu, W. Koh, S. Kim, H. Y. Soh, N. E. Waminal, H. R. Belandres, J. Y. Lim, G. Yi, J. H. Ahn, J.-S. Kim, Y.-M. Kim, , J. H. Huh

This study investigates how genome divergence and compatibility contribute to the stabilization of hybrid genomes in an allopolyploid plant species.

bioRxiv · Sep 28, 2021 · PreprintPlant Biology

Comparative phylogenomic analysis reveals evolutionary genomic changes and novel toxin families in endophytic Liberibacter pathogens

D. Zhang, Y. Tan, C. Wang, T. Schneider, H. Li, R. F. de Souza, X. Tang, T.-F. Hsieh, X. Wang, X. Li

This study identifies genomic changes and novel toxins in Liberibacter pathogens through comparative phylogenomic analysis, linking prophage loci and gene gains/losses to pathogenicity.

bioRxiv · Jun 2, 2021Microbiology

The Catalytic Core of DEMETER Guides Active DNA Demethylation in Arabidopsis

C. Zhang, Y.-H. Hung, X.-Q. Zhang, D. Zhang, J. M. Frost, F. Liu, W. Xiao, L. M. Iyer, L. Aravind, J. H. Huh, R. L. Fischer, T.-F. Hsieh

This study identifies the catalytic core of DME as essential for active DNA demethylation in Arabidopsis, showing that the N-terminus is required for heterochromatin demethylation and specificity.

bioRxiv · May 1, 2019Plant Biology