Author
Helmholtz Centre for Infection Research
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Katharina G. Wandera, Stefan Schmelz, Angela Migur…·Chase L. Beisel
This paper shows AcrVIB1 inhibits CRISPR-Cas13b by promoting unproductive crRNA binding and degradation, revealing a mechanism to suppress immune defense.
Constantinos Patinios, Darshana Gupta, Harris V. Bassett…·Chase L. Beisel
This paper introduces append editing, a method that uses ADP-ribosylation to achieve distinct genome editing outcomes in bacteria and eukaryotes.
Daphne Collias, Elena Vialetto, Jiaqi Yu…·Chase L. Beisel
This paper shows that reducing DNA targeting activity in CRISPR systems improves genome editing efficiency in bacteria by enabling RecA-mediated repair.
Angelo Cardoso Batista, Antoine Lévrier, Paul Soudier…·Manish Kushwaha
This paper develops exonuclease-deficient cell-free extracts and optimized buffers to enable robust expression from unprotected linear DNA without additional protection strategies.