Author

Tejaswini Karra

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander von AppeniD· 1 shared Alvaro Dominguez‐Baquero· 1 shared Andrew G. NewmaniD· 1 shared Bilge AskiniD· 1 shared Boglarka Krisztina Nagy-HerczegiD· 1 shared Cagla Kilic· 1 shared Chiara BordieriD· 1 shared Cong WangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexander von AppenORCID

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2 papers

Recent·Most cited

Insulin resistance alters cortical inhibitory neurons and microglia to exacerbate Alzheimer knock-in mouse phenotypes

LaShae Nicholson, Si Jie Tang, Tejaswini Karra, Habiba Abouelatta, Stephen M. Strittmatter

This study shows that a high-fat, high-sugar diet worsens cognitive deficits in Alzheimer's mouse models through metabolic stress in specific brain cells, independent of amyloid or tau pathology.

Molecular Neurodegeneration · Jun 3, 2026Peer-reviewedNeuroscience

Tau modulates nuclear integrity, chromatin, and cholesterol synthesis genes via the nuclear envelope

Lisa Diez, Renata Ponce-Lina, Cagla Kilic, Rithika Sankar, Frieda Balduin, Cong Wang, Pia Grundschöttel, Koki Sakurai, Bilge Askin, Chiara Bordier, Tejaswini Karra, Katharina Tipp, Boglarka Krisztina Nagy-Herczeg, Maryam Mohamaddokht, Leandre M. Ravatt, , Susanne Wegmann

This study shows that increased somatodendritic Tau interacts with nuclear envelope proteins, causing nuclear damage and altering gene expression related to AD and tauopathies.

bioRxiv · Feb 14, 2026 · PreprintNeuroscience