Author
University of EdinburghORCID 0000-0002-5397-3864Unclaimed ORCID profile · follow to get notified of new preprints
10 papers
Recent·Most cited
Alex D. McLachlan, Rob Court, Clare Pilgrim, Kit D. Longden, Nicolas H. Brown, David Osumi-Sutherland, Gregory S.X.E. Jefferis, J. Douglas Armstrong
Model Context Protocol tools over Virtual Fly Brain's graph let Claude answer 25/30 Drosophila neuroscience tasks precisely, vs 14/30 with web search, 2/30 bare.
bioRxiv · Jul 14, 2026 · PreprintNeuroscience✦ In-depth digest
Oksana Sorokina, Edita Bulovaite, Anatoly Sorokin, Seth G. N. Grant, J. Douglas Armstrong
The paper develops computational models to explain synaptic protein distribution patterns in neurons by integrating molecular transport and local synaptic demand mechanisms across different ages and cell types.
Scientific Reports · Mar 2, 2026Peer-reviewedNeuroscience
Oksana Sorokina, Digin Dominic, Àlex Bayés, J. Douglas Armstrong, Seth G. N. Grant
SynaptopathyDB integrates synapse proteomic and genetic data to identify synaptic gene variants associated with neurological and systemic disorders.
bioRxiv · Jun 27, 2025 · PreprintNeuroscience
Rasneer Sonia Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, Patrick M. Nolan, Sara E. Wells
This study uses home-cage video tracking to analyze voluntary behaviors in mice, revealing complex phenotypes and sexual dimorphism in a Huntington's disease model.
bioRxiv · Jan 19, 2023 · PreprintNeuroscience
Francesco Oliva, Francesco Musiani, Alejandro Giorgetti, Silvia De Rubeis, Oksana Sorokina, J. Douglas Armstrong, Paolo Carloni, Paolo Ruggerone
MoNvIso predicts the correct protein isoform for mutations and builds structural models of wild-type and variant isoforms using gene names and mutation lists.
Frontiers in Chemistry · Jan 9, 2023Peer-reviewedBioinformatics
C. Mclean, Anatoly Sorokin, T. Ian Simpson, J. Douglas Armstrong, Oksana Sorokina
BioNAR is a Bioconductor package for analyzing biological networks to quantify and rank vertices based on topology and clustering, enabling discovery of disease and function-enriched subcomplexes.
Bioinformatics Advances · Jan 1, 2023Peer-reviewedBioinformatics
Rob Court, Shigehiro Namiki, J. Douglas Armstrong, Jana Börner, Gwyneth M Card, Marta Costa, Michael H. Dickinson, Carsten Duch, Wyatt L. Korff, Richard S. Mann, David John Merritt, Rod K Murphey, Andrew Michael Seeds, Troy R. Shirangi, Julie H. Simpson, , David Shepherd
The paper provides a systematic nomenclature for the Drosophila ventral nervous system, extending an existing framework to include thoracic and abdominal neuromeres.
Neuron · Sep 1, 2020Peer-reviewedNeuroscience
Lindsey J. Caldwell, Nick O. Davies, Leonardo Cavone, Karolina Sandra Mysiak, Svetlana A. Semenova, Pertti Panula, J. Douglas Armstrong, Catherina Gwynne Becker, Thomas Becker
The paper shows that adult zebrafish regenerate dopaminergic neurons, but this capacity varies between populations and depends on immune system activation.
Journal of Neuroscience · Apr 4, 2019Peer-reviewedNeuroscience
Marcia M. Roy, Oksana Sorokina, C. Mclean, Silvia Tapia‐González, Javier DeFelipe, J. Douglas Armstrong, Seth G. N. Grant
The paper identifies regional differences in the postsynaptic proteome across mouse brain regions using proteomic mass spectrometry, revealing unique compositional signatures correlated with anatomy and embryology.
Proteomes · Aug 1, 2018Peer-reviewedNeuroscience
Katharina F. Heil, Emilia Wysocka, Oksana Sorokina, Jeanette Hellgren Kotaleski, T. Ian Simpson, J. Douglas Armstrong, David C. Sterratt
The paper maps proteins in biophysical models of synaptic plasticity, finding 4.2% of synaptic proteins are modelled and identifying gaps in disease-related proteins.
bioRxiv · Jan 28, 2018 · PreprintNeuroscience