Author

Tzu-Yi Chia

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jason M. MiskaiD· 3 shared Amy B. HeimbergeriD· 2 shared Atique U. AhmediD· 2 shared Catalina Lee-ChangiD· 2 shared Hinda NajemiD· 2 shared Lauren K. BolandiD· 2 shared Leah K. BillinghamiD· 2 shared Peng ZhangiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Jason M. MiskaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth

Kalil G. Abdullah, Kenji Miki, Charles K. Edgar, Shuangcheng Alivia Wu, Yi Xiao, Yuan-Tai Huang, Richard Drexler, Saritha Krishna, Vineshkumar Thidil Puliyappadamba, Li Wei Rachel Tay, Fanen Yuan, Milan R. Savani, Maged T Ghoche, Shawn E. Kotermanski, Jeffrey Isaac Traylor, , Samuel K. McBrayer

This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.

Cell · Sep 1, 2026Peer-reviewedCancer Biology

Myeloid-targeted RNA nanotherapeutics rewire cholesterol metabolism to unleash anti-tumor immunity in glioblastoma

Jiawei Huo, Hanchen Lin, Yinmeng Li, Shashwat Tripathi, Rafał Chojak, Caylee Silvers, Yirui Peng, Lauren K. Boland, Jianzhong Zhang, Kathleen McCortney, Rasangi M. Perera, Hinda Najem, Leah K. Billingham, Tzu-Yi Chia, Xiaoyang Chen, , Peng Zhang

The paper develops RNA nanotherapeutics targeting TAMC cholesterol metabolism to enhance anti-tumor immunity in glioblastoma.

bioRxiv · Aug 7, 2026 · PreprintImmunology

Microglial Fructose Metabolism Is Essential for Glioblastoma Growth

Leah K. Billingham, Susan L DeLay, Yasmina Eshac, Tzu-Yi Chia, Shashwat Tripathi, Ian E Olson, Kaylee Zilinger, Jay Subbiah, Zhaoquan Wang, Nishanth S. Sadagopan, Hinda Najem, Guillaume Cognet, Joshua L. Katz, Ruochen Du, Khizar Rehan Nandoliya, , Jason M. Miska

This study shows that microglial fructose metabolism via GLUT5 is critical for glioblastoma growth, as GLUT5-KO mice live longer with reduced tumor progression.

Proceedings of the National Academy of Sciences · Mar 17, 2026Peer-reviewedCancer Biology