Author

V. L. Butty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

S. S. Levine· 2 shared A. I. Ponomarenko· 1 shared A. K. Shalek· 1 shared A. M. Phillips· 1 shared C. B. Ogbunugafor· 1 shared C. Whittaker· 1 shared D. H. Kim· 1 shared E. E. Nekongo· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

S. S. Levine

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gene signatures and host-parasite interactions revealed by dual single-cell profiling of Plasmodium vivax liver infection

L. Mancio-Silva, N. Gural, M. H. Wadsworth, V. L. Butty, T. K. Hughes, S. March, N. Nerurkar, W. Roobsoong, H. E. Fleming, C. Whittaker, S. S. Levine, J. Sattabongkot, A. K. Shalek, S. N. Bhatia

This study uses single-cell profiling to analyze P. vivax liver infection, identifying host and parasite transcriptional signatures and revealing new insights into parasite dormancy and host responses.

bioRxiv · Sep 1, 2021 · PreprintMicrobiology

The Host Cell's Endoplasmic Reticulum Proteostasis Network Profoundly Shapes the Protein Sequence Space Accessible to HIV Envelope

J. Yoon, E. E. Nekongo, J. E. Patrick, A. M. Phillips, A. I. Ponomarenko, S. J. Hendel, V. L. Butty, C. B. Ogbunugafor, Y.-S. Lin, M. D. Shoulders

This study shows that upregulating the host ER proteostasis network via the UPR reduces mutational tolerance of HIV Env, with some regions becoming more tolerant, suggesting host proteostasis influences HIV adaptation.

bioRxiv · Apr 24, 2021Biochemistry

Global transcriptional regulation of innate immunity in C. elegans

M. Fletcher, E. J. Tillman, V. L. Butty, S. S. Levine, D. H. Kim

The paper identifies ATF-7 as a key transcriptional regulator of the innate immune response in C. elegans through genomic analysis of pathogen-induced gene regulation.

bioRxiv · Nov 13, 2018Immunology