Author

V. Olexiouk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Decaesteker· 2 shared C. Van Neste· 2 shared D. Deforce· 2 shared F. Speleman· 2 shared F. Van Nieuwerburgh· 2 shared J. Van Laere· 2 shared K. Durinck· 2 shared L. M. Mus· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

B. Decaesteker

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Author profile →

3 papers

Recent·Most cited

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

S. Zanotti, S. Vanhauwaert, C. Van Neste, V. Olexiouk, J. Van Laere, M. Verschuuren, L. M. Mus, K. Durinck, L. Tilleman, D. Deforce, F. Van Nieuwerburgh, M. D. Hogarty, B. Decaesteker, W. H. De Vos, F. Speleman

This study shows that MYCN activation in RPE cells causes nucleolar stress and a senescence-like transcriptional program without full senescence hallmarks, leading to growth attenuation.

bioRxiv · Jan 22, 2021Cancer Biology

RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma

C. Nunes, L. Depestel, L. M. Mus, K. M. Keller, L. Delhaye, A. Louwagie, M. Rishfi, E. M. Dolman, V. Olexiouk, C. Bartenhagen, F. Devloed, E. Sanders, A. Eggermont, J. Van Laere, E. De Smet, , F. Speleman

This study identifies RRM2 as a therapeutic target in high-risk neuroblastoma, showing that combined RRM2 and CHK1 inhibition synergistically reduces tumor growth.

bioRxiv · Nov 25, 2020 · PreprintCancer Biology

BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

S. Zhang, C. Liang, C. Mary, B. Kerouantan, J. Francisco, N. S. Jagannathan, V. Olexiouk, J. H. Peh, C. Tang, G. Fidelito, S. Nama, R.-K. Cheng, C. L. Wee, L. C. Wang, P. D. Roggli, , L. Ho

The paper identifies BRAWNIN, a sORF-encoded peptide critical for vertebrate mitochondrial complex III assembly, showing its role in oxidative phosphorylation and metabolic function.

bioRxiv · Jan 31, 2020 · PreprintCell Biology