Author

V. Shabardina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

I. Ruiz-Trillo· 2 shared A. Cuenda· 1 shared A. D. Gitler· 1 shared A. Marian· 1 shared A. Sanyal· 1 shared E. Diaz-Mora· 1 shared E. Kabashi· 1 shared G. Auburger· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersEvolutionary Biology

I. Ruiz-Trillo

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Author profile →

3 papers

Recent·Most cited

Evolutionary analysis of p38 stress-activated kinases in unicellular relatives of animals suggests an ancestral function in osmotic stress

V. Shabardina, P. R. Charria, G. B. Saborido, E. Diaz-Mora, A. Cuenda, I. Ruiz-Trillo, J. J. Sanz-Ezquerro

This study investigates the evolutionary origin and diversification of p38 kinases in animals and fungi, showing their ancestral role in osmotic stress response and subsequent functional expansion in animals.

bioRxiv · Apr 24, 2022Evolutionary Biology

Poly(A)-binding protein is an ataxin-2 chaperone that emulsifies biomolecular condensates.

S. Boeynaems, Y. Dorone, A. Marian, V. Shabardina, G. Huang, G. Kim, A. Sanyal, N.-E. Sen, R. Docampo, I. Ruiz-Trillo, K. Lasker, G. Auburger, E. Kabashi, A. D. Gitler

The paper identifies a conserved 14aa sequence in ataxin-2 that acts as a condensation switch and reveals poly(A)-binding proteins as RNA-dependent chaperones that regulate this switch.

bioRxiv · Aug 23, 2021 · PreprintCell Biology

Emergence and evolution of the ERM proteins and merlin in metazoans

V. Shabardina, Y. Kashima, Y. Suzuki, W. Makalowski

The paper performs a phylogenetic analysis of ERM proteins and merlin across 87 species, revealing their evolutionary origins, diversification, and functional adaptations, including tumor suppression.

bioRxiv · Sep 8, 2019Evolutionary Biology