Author

Vilma Barroca

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Françoise PflumioiD· 2 shared Laurent RenouiD· 2 shared Nathalie Déchamps· 2 shared Alex MaasiD· 1 shared Alexandra ChicheporticheiD· 1 shared Arnaud PetitiD· 1 shared Benjamin DemailleiD· 1 shared Benjamin UzaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Françoise PflumioORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Transplantation in neonate mouse recipients enhances umbilical cord blood CD34+ cells permissiveness to ETO2::GLIS2-driven transformation

Klaudia Galant, Vilma Barroca, Saiyirami Devanand, Didier Busso, Guillaume Piton, Nathalie Déchamps, Laurent Renou, Thomas Mercher, Stéphanie Gachet, Françoise Pflumio

This study shows that neonatal mouse recipients are more permissive than adult mice for ETO2::GLIS2-driven leukemogenesis from human cord blood CD34+ cells.

bioRxiv · Jan 13, 2026 · PreprintCancer Biology

In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in beta-thalassemia

Virginie Deleuze, Tharshana Stephen, Mohammad Salma, Cédric Orfeo, Ruud Jorna, Alex Maas, Vilma Barroca, Marie-Laure Arcangeli, Charles‐Henri Lecellier, Charlotte Andrieu‐Soler, Frank G. Grosveld, Éric Soler

The paper investigates the functional impact of a GWAS-identified Myb enhancer in beta-thalassemia by generating a knock-out mouse model and analyzing its effects on erythropoiesis and clinical parameters.

Scientific Reports · Mar 15, 2025Peer-reviewedGenetics

Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis

Corentin Bernou, Marc‐André Mouthon, Mathieu Daynac, Thierry Kortulewski, Benjamin Demaille, Vilma Barroca, Sébastien Couillard‐Després, Nathalie Déchamps, Véronique Ménard, Léa Bellenger, Christophe Antoniewski, Alexandra Chicheportiche, François Dominique Boussin

The paper identifies an immature neuroblast population with plasticity and molecular switches in splicing regulators during neurogenesis.

eLife · Nov 22, 2024Peer-reviewedGenomics

T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including Hepatocyte Growth factor

Charly Le Maout, Lucine Fahy, Laurent Renou, Caroline Devanand, Charlotte Duwat, Vilma Barroca, Morgane Le Gall, Paola Fabiola Ballerini, Arnaud Petit, Julien Calvo, Benjamin Uzan, Françoise Pflumio, Vanessa Petit

This study identifies an inflammatory microenvironment in T-ALL that supports progression, with HGF as a potential therapeutic target.

Biomedicine & Pharmacotherapy · Jul 1, 2024Peer-reviewedCancer Biology

shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination

Cynthia Petrillo, Vilma Barroca, Jonathan Ribeiro, Nathalie Lailler, Gabriel Livera, Scott Keeney, Emmanuelle M.-D Martini, Devanshi Jain

This study identifies a mutation in mouse Spata22 that disrupts splicing, leading to impaired meiotic recombination and sterility.

Chromosoma · May 10, 2020Peer-reviewedGenetics