YY2/BUB3 axis-mediated SAC hyperactivity determines tumor cell fate through chromosomal instability
R. Hosea, W. Duan, I. T. S. Meliala, W. Li, M. Wei, S. Hillary, H. Zhao, M. Miyagishi, S. Wu, V. Kasim
This study identifies the YY2/BUB3 axis as a regulator of SAC activity and shows how SAC hyperactivity and CIN levels influence tumor cell fate and drug sensitivity.
bioRxiv · Oct 7, 2023 · PreprintCancer Biology