Author

W. J. Huh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

R. J. Coffey· 3 shared A. E. Zemper· 1 shared A. J. Simmons· 1 shared A. N. Southard-Smith· 1 shared B. Chen· 1 shared C. L. Sears· 1 shared C. N. Heiser· 1 shared E. T. McKinley· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPathology

R. J. Coffey

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Author profile →

3 papers

Recent·Most cited

Transcriptomic Profiling Reveals Claudin 18.2 as a Diagnostic Biomarker of Menetrier Disease and the Role of Hedgehog Signaling in Pathogenesis

M. Shin, T. Gabriel, R. J. Coffey, W. J. Huh

This study identifies CLDN18.2 as a diagnostic marker for Menetrier Disease and shows that Hedgehog signaling is upregulated and therapeutically targetable in the disease.

bioRxiv · Nov 3, 2023 · PreprintPathology

Lrig3 restricts the size of the colon stem cell compartment

J. M. Stevenson, R. Sayegh, N. Pedicino, N. A. Pellitier, T. M. Wheeler, M. E. Bechard, W. J. Huh, R. J. Coffey, A. E. Zemper

This study shows that Lrig3 limits the size of the colon stem cell compartment by regulating cell number and crypt structure in mice.

bioRxiv · Mar 8, 2022 · PreprintCell Biology

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

bioRxiv · Jan 11, 2021Cancer Biology