Author

W. Y. Aw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. J. Hickey· 2 shared E. L. Doherty· 2 shared W. J. Polacheck· 2 shared A. H. Cooper· 1 shared A. Hatimy· 1 shared A. Hickey· 1 shared B. Griffith· 1 shared B. O. Diekman· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

A. J. Hickey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics

E. L. Doherty, W. Y. Aw, E. C. Warren, M. Hockenberry, G. Krohn, S. D. Howell, B. O. Diekman, W. R. Legant, H. T. Nia, A. Hickey, W. J. Polacheck

The paper shows that COL3A1 mutations alter ECM composition and mechanical properties, affecting endothelial cell migration and suggesting ECM mechanics as a prognostic indicator for vEDS.

bioRxiv · Oct 16, 2022Bioengineering

Microphysiological vascular malformation model reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.

W. Y. Aw, C. Cho, H. Wang, A. H. Cooper, E. L. Doherty, D. Rocco, S. A. Huang, S. Kubik, C. P. Whitworth, R. Armstrong, A. J. Hickey, B. Griffith, M. L. Kutys, J. Blatt, W. J. Polacheck

The paper develops a microfluidic model of PIK3CA-driven vascular malformations and identifies dysregulated Rac1/PAK and mTORC1/2 signaling as key factors in lesion formation.

bioRxiv · Sep 3, 2022 · PreprintBioengineering

The ataxia protein sacsin is required for integrin trafficking and synaptic organization

L. E. L. Romano, W. Y. Aw, K. M. Hixson, T. V. Novoselova, T. M. Havener, S. Howell, C. L. Hall, L. Xing, J. Beri, S. Nethisinghe, L. Perna, A. Hatimy, G. Chioccioli Altadonna, L. M. Graves, L. E. Herring, , J. M. Wolter

This study identifies sacsin's role in integrin trafficking and synaptic organization, showing its deficiency causes cellular phenotypes in ARSACS.

bioRxiv · Aug 20, 2021 · PreprintCell Biology