Author

Wen Fan

Emory UniversityPrimary ORCID profile (0000-0001-5224-6895 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Wen FaniD1 paper · Nanjing Medical University

Biology Disciplines

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Genetics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Aliza P. WingoiD· 3 shared Allan I. LeveyiD· 3 shared David Alan BennettiD· 3 shared Ekaterina Sergeevna GerasimoviD· 3 shared James J. LahiD· 3 shared Nicholas T. SeyfriediD· 3 shared Thomas S. WingoiD· 3 shared Duc Minh DuongiD· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Aliza P. WingoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic control of the human brain proteome

Chloe Robins, Yue Liu, Wen Fan, Duc Minh Duong, Jacob Meigs, Nadia V. Harerimana, Ekaterina Sergeevna Gerasimov, Eric B. Dammer, David J. Cutler, Thomas G. Beach, Eric M. Reiman, Philip L. De Jager, David Alan Bennett, James J. Lah, Aliza P. Wingo, , Thomas S. Wingo

The paper identifies pQTLs for brain proteins and finds they differ from eQTLs, suggesting distinct genetic control of mRNA and protein abundance.

The American Journal of Human Genetics · Feb 10, 2021Peer-reviewedGenetics

Cerebral atherosclerosis contributes to Alzheimer’s dementia independently of its hallmark amyloid and tau pathologies

Aliza P. Wingo, Wen Fan, Duc Minh Duong, Ekaterina Sergeevna Gerasimov, Eric B. Dammer, Yue Liu, Nadia V. Harerimana, Bartholomew White, Madhav Thambisetty, Juan Carlos Troncoso, Namhee Kim, Julie A. Schneider, Ihab M. Hajjar, James J. Lah, David Alan Bennett, , Thomas S. Wingo

This study identifies 114 proteins and 5 modules linked to cerebral atherosclerosis in the brain, with 23 proteins and 2 modules also associated with Alzheimer’s dementia, highlighting shared mechanisms involving synaptic signaling and myelination.

Nature Neuroscience · May 18, 2020Peer-reviewedNeuroscience

Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

Thomas S. Wingo, Jingjing Yang, Wen Fan, Se Min Canon, Ekaterina Sergeevna Gerasimov, Adriana Lori, Benjamin A. Logsdon, Bing Yao, Nicholas T. Seyfried, James J. Lah, Allan I. Levey, Patricia A. Boyle, Julia A. Schneider, Philip L. De Jager, David Alan Bennett, Aliza P. Wingo

The paper identifies brain microRNAs linked to late-life depressive symptoms and shows their association with cognitive decline and dementia risk.

npj Genomic Medicine · Feb 6, 2020Peer-reviewedGenomics