Author

Bartholomew White

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

David A. A BennettiD· 3 shared Allan I. LeveyiD· 2 shared Duc Minh DuongiD· 2 shared Eric B. DammeriD· 2 shared Ihab M. HajjariD· 2 shared James J. LahiD· 2 shared Juan Carlos TroncosoiD· 2 shared Madhav ThambisettyiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

David A. A BennettORCID

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Author profile →

3 papers

Recent·Most cited

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease

Isabel Castanho, Pourya Naderi Yeganeh, Carles A. Boix, Sarah L. Morgan, Hansruedi Mathys, Dmitry Prokopenko, Bartholomew White, Larisa M. Soto, Giulia Pegoraro, Saloni A. Shah, Athanasios Ploumakis, Nikolaos Kalavros, David A. A Bennett, Christoph Lange, Doo Yeon Kim, , Winston Hide

This study identifies molecular and cellular signatures of cognitive resilience in Alzheimer's disease by integrating multi-omics data from brain tissues.

bioRxiv · Jan 13, 2025 · PreprintNeuroscience

Cerebral atherosclerosis contributes to Alzheimer’s dementia independently of its hallmark amyloid and tau pathologies

Aliza P. Wingo, Wen Fan, Duc Minh Duong, Ekaterina Sergeevna Gerasimov, Eric B. Dammer, Yue Liu, Nadia V. Harerimana, Bartholomew White, Madhav Thambisetty, Juan Carlos Troncoso, Namhee Kim, Julie A. Schneider, Ihab M. Hajjar, James J. Lah, David Alan Bennett, , Thomas S. Wingo

This study identifies 114 proteins and 5 modules linked to cerebral atherosclerosis in the brain, with 23 proteins and 2 modules also associated with Alzheimer’s dementia, highlighting shared mechanisms involving synaptic signaling and myelination.

Nature Neuroscience · May 18, 2020Peer-reviewedNeuroscience

A Consensus Proteomic Analysis of Alzheimer's Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

Erik C. B. Johnson, Eric B. Dammer, Duc Minh Duong, Lingyan Ping, Maotian Zhou, Luming Yin, Lenora A. Higginbotham, Andrew Guajardo, Bartholomew White, Juan Carlos Troncoso, Madhav Thambisetty, Thomas Jude Montine, Edward B. Lee, John Q. Trojanowski, Thomas G. Beach, , Nicholas T. Seyfried

The paper identifies protein network modules in Alzheimer's disease brains and cerebrospinal fluid that are associated with energy metabolism and neuroinflammation, suggesting potential biomarkers and therapeutic targets.

Nature Medicine · Apr 13, 2020Peer-reviewedSystems Biology