Engineering One-Signal Activated TILs with CD3ζ-CD28 Chimeras Optimizes the Antitumor Efficacy of TIL-Based Immunotherapy
Y. Wu, x. s. ye, Y. Zhu, S. Liu, J. Song, Y. Zhang, Q. Yuan, F. Liu, D. Kong, L. Zhao
This paper engineers one-signal-activated TILs with CD3ζ-CD28 chimeras to enhance antitumor efficacy in immunotherapy.
bioRxiv · Mar 21, 2024 · PreprintImmunology