Author

X. Xia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 6 Pharmacology & Toxicology· 5 Biophysics· 4 Cell Biology· 4 Microbiology· 4 Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 26 Research Focus:cell type annotation· 14 Organism:mouse· 10 Research Focus:differential expression· 9 Organism:human· 9 Approach:statistical model· 9 Research Focus:cell signaling & trafficking· 7 Research Focus:drug response / drug discovery· 7

Frequent Co-Authors

J. Wang· 4 shared J. Zhang· 4 shared Y. Zhang· 4 shared C. J. Lingle· 3 shared H. Cao· 3 shared H. Ding· 3 shared H. Liu· 3 shared Y. Gao· 3 shared

Activity by Year

2016-2024 · peak 11/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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4 shared papersCell Biology

J. Wang

Mutual co-authors in cluster

Author profile →

37 papers

Recent·Most cited

The PK/PD Integration and Resistance of Ti lmi cosin Against Mycoplasma hyopneumoniae

H. Ding, Z. Huang, Z. Hu, X. Xia, H. Zheng, X. Gu, X. Shen, H. Yang

This study investigates the PK/PD relationship of tilmicosin against M. hyopneumoniae, identifies resistance mechanisms, and suggests optimal dosing regimens.

bioRxiv · Mar 4, 2020Pharmacology & Toxicology

Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning：esophageal cancer as an example

S. Liu, J. Wu, Q. Xia, H. Liu, W. Li, X. Xia, J. Wang

This study identifies new epigenetic and genetic biomarkers for esophageal cancer using cfDNA and combines SALP-seq with machine learning.

bioRxiv · Jan 18, 2020Cancer Biology

Volumetric two-photon imaging in live cells and embryos via axially gradient excitation

Y. Gao, X. Xia, J. Yu, T. Chen, Z. Xu, L. Xiao, L. Wang, F. Yan, Z. Du, J. Chu, H. Zheng, H. Li, W. Zheng

This paper introduces a gradient two-photon microscopy technique that enables rapid volumetric imaging with reduced phototoxicity by using two axially gradient excitation beams.

bioRxiv · Mar 27, 2019 · PreprintBioengineering

Comprehensive proteomic and metabolomic profiling of mcr-1 mediated colistin resistance in Escherichia coli

H. Li, Y. Wang, Q. Meng, Y. Wang, G. Xia, X. Xia, J. Shen

This study identifies proteomic and metabolomic changes in Escherichia coli mediated by mcr-1, showing altered lipid metabolism and efflux pump activity contribute to colistin resistance.

bioRxiv · Oct 3, 2018Pharmacology & Toxicology

BK channel inhibition by strong extracellular acidification

Y. Zhou, X. Xia, C. J. Lingle

This study shows that extracellular acidification strongly inhibits BK channel activation by shifting its conductance-voltage relationship and blocking voltage-sensor activation through specific acidic residues.

bioRxiv · May 8, 2018Biophysics

Genetic Diversity and Distributional Pattern of Ammonia Oxidizing Archaea Lineages in the Global Oceans

S. Y. Cheung, W. Mak, X. Xia, Y. Lu, H. Liu

The paper analyzes the distribution and genetic diversity of ammonia-oxidizing archaea (AOA) lineages in global oceans using metagenomics data, revealing distinct ecological patterns and environmental correlations.

bioRxiv · Jan 17, 2018Ecology

Exploring the mutational robustness of nucleic acidsby searching genotype neighbourhoods in sequencespace

Q. Zhou, X. Sun, X. Xia, Z. Fan, Z. Luo, S. Zhao, H. Liang, E. Shakhnovich

The paper uses in silico SELEX to study mutational robustness of an L-Arm binding aptamer, finding two functional genotype neighborhoods with similar binding affinity to the wild-type.

bioRxiv · Dec 3, 2016Evolutionary Biology