Author

Xinyue Wang

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 2 Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Brian J. BacskaiiD· 1 shared Cara R Adolph· 1 shared Cassandra L. Chapman· 1 shared David HikeiD· 1 shared Fengmin Yang· 1 shared Greg Cook· 1 shared Huan Chen· 1 shared Jinyao Liu· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperNeuroscience

Brian J. BacskaiORCID

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Author profile →

4 papers

Recent·Most cited

High-throughput genetic interaction analysis in Mycobacterium tuberculosis identifies highly synergistic drug targets

Cassandra L. Chapman, XinYue Wang, Cara R Adolph, Peter C. Fineran, Greg Cook, Simon A. Jackson, Matthew McNeil

This study uses CRISPRi screening in Mycobacterium tuberculosis to identify synergistic drug targets, finding that genetic interactions predict drug-drug synergies and identifying Pks13 as a key synergistic generalist.

bioRxiv · Oct 15, 2026 · PreprintMicrobiology

Vessel-Resolved Mapping of Perivascular Spaces Reveals Hierarchical Neurofluid Organization In Vivo

Xiaoqing Alice Zhou, Xiaochen Liu, Weitao Man, Sang-Cheon Choi, David Hike, Xinyue Wang, Yuanyuan Jiang, Maiken Nedergaard, Kristopher Thomas Kahle, Brian J. Bacskai, Xin Yu

This paper introduces an ultra-high-resolution MRI framework to map perivascular spaces (PVS) across the whole brain, revealing their hierarchical organization along vascular trees.

bioRxiv · May 5, 2026 · PreprintNeuroscience

Promoter-Driven Modulation of Flagellin Expression and Motility in Escherichia coli

Karima Bharati Bayana, Xinyue Wang

This paper demonstrates the ability to control bacterial motility in Escherichia coli by engineering promoters to modulate flagellin expression, showing non-linear relationships and optimal motility at 30°C.

bioRxiv · Jan 31, 2025 · PreprintSynthetic Biology

Clostridium ablates tumors by degrading collagen mesh andinducing ferroptosis

Fengmin Yang, Lu Meng, Huan Chen, Xinyue Wang, Mengmeng Zhang, Zhenping Cao, Yan Pang, Jinyao Liu

This paper describes a Clostridium strain that degrades collagen and induces ferroptosis in tumors, leading to effective tumor destruction in mice.

bioRxiv · May 15, 2024 · PreprintMicrobiology