Author

Y. Alippe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Wang· 2 shared G. Mbalaviele· 2 shared J. Xiao· 2 shared K. Sun· 2 shared T. Yang· 2 shared Y. Abu-Amer· 2 shared C. Xu· 1 shared D. Hao· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

C. Wang

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2 papers

Recent·Most cited

Fracture healing is delayed in the absence of gasdermin signaling

G. Mbalaviele, K. Sun, C. Wang, J. Xiao, M. D. Brodt, L. Yuan, T. Yang, Y. Alippe, H. Hu, D. Hao, Y. Abu-Amer, M. Silva, J. Shen

This study shows that gasdermin signaling is essential for fracture healing, as its absence delays bone callus formation and reduces biomechanical properties.

bioRxiv · Nov 29, 2021Immunology

Activation of GSDME compensates for GSDMD deficiency in a mouse model of NLRP3 inflammasomopathy

C. Wang, T. Yang, J. Xiao, C. Xu, Y. Alippe, K. Sun, T.-D. Kanneganti, J. B. Monahan, Y. Abu-Amer, J. Lieberman, G. Mbalaviele

This study shows that GSDME compensates for GSDMD deficiency in NLRP3 inflammasomopathy, revealing a GSDME-dependent inflammatory pathway and suggesting dual inhibition of GSDMD and GSDME for therapeutic benefit.

bioRxiv · Jan 6, 2021 · PreprintImmunology