Author

Y. Chinenov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

I. Rogatsky· 2 shared M. Dacic· 2 shared N. Schwartz· 2 shared T. T. Lu· 2 shared W. D. Shipman· 2 shared W. G. Ambler· 2 shared A. B. Pernis· 1 shared A. Daamen· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

I. Rogatsky

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Author profile →

5 papers

Recent·Most cited

Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid and IL4-Driven Macrophage Programming

D. K. Deochand, M. Dacic, M. J. Bale, A. W. Daman, S. Z. Josefowicz, D. Oliver, Y. Chinenov, I. Rogatsky

This study identifies shared and distinct mechanisms of macrophage programming by IL4 and glucocorticoids, revealing GRIP1's role in integrating their effects on transcription and function.

bioRxiv · Feb 16, 2024Immunology

Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses

M. J. Howlader, W. G. Ambler, M. L. S. Chalasani, A. Rathod, E. Seltzer, J. Sim, J. Shin, N. Schwartz, W. D. Shipman, D. Dasoveanu, C. Carballo, E. Sevim, S. Siddique, Y. Chinenov, S. Rodeo, , T. T. Lu

This study shows that lymphatic dysfunction in lupus exacerbates cutaneous photosensitivity and lymph node B cell responses, and that improving lymphatic flow reduces these effects.

bioRxiv · Jun 13, 2022Immunology

The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

T. M. Li, V. Zyulina, E. S. Seltzer, M. Dacic, Y. Chinenov, A. Daamen, K. R. Veiga, N. Schwartz, D. J. Oliver, J. Lora, A. Jabbari, Y. Liu, W. D. Shipman, W. G. Ambler, S. F. Taber, , T. T. Lu

This study shows that IFN-I in lupus skin reduces Langerhans cell ADAM17 activity, leading to increased photosensitivity, and that anti-IFNAR treatment restores ADAM17 function and reduces photosensitivity.

bioRxiv · Aug 18, 2021Immunology

Sex-specific differences in the function and differentiation of ABCsmark TLR7-driven immunopathogenesis

E. Ricker, M. Manni, D. Flores-Castro, D. Jenkins, S. Gupta, J. Rivera-Correa, W. Meng, A. M. Rosenfeld, T. Pannellini, M. Bachu, Y. Chinenov, P. K. Sculco, R. Jessberger, E. T. Luning Prak, A. B. Pernis

The paper shows sex-specific differences in ABCs expansion, ISG signature upregulation, and differentiation in TLR7-driven immunopathogenesis, with Tlr7 duplication in males exacerbating disease severity.

bioRxiv · Jan 20, 2021 · PreprintImmunology

Age-related Impairment of Implant Osseointegration is Associated with Immune Activation and Suppression of Angiogenic, Notch, and Wnt Pathways

K. Turajane, G. Ji, Y. Chinenov, M. Chao, U. M. Ayturk, M. B. Greenblatt, L. B. Ivashkiv, M. P. G. Bostrom, X. Yang

This study identifies age-related downregulation of angiogenic, Notch, and Wnt pathways in peri-implant tissue, linked to immune activation and impaired osseointegration in aged mice.

bioRxiv · Dec 27, 2020 · PreprintImmunology