Author

Y. Quan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Zhou· 3 shared S. M. Hinshaw· 2 shared A. H. Wong· 1 shared A. T. Whiteley· 1 shared A. Wu· 1 shared A. Zhou· 1 shared B. Huang· 1 shared C. Deng· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersCell Biology

H. Zhou

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling

H. E. Ledvina, Q. Ye, Y. Gu, Y. Quan, R. K. Lau, H. Zhou, K. D. Corbett, A. T. Whiteley

The paper shows that a bacterial E1-E2 fusion protein, Cap2, primes cGAS for antiviral signaling through a process called cGASylation, which increases cGAMP production by ~50-fold.

bioRxiv · Mar 31, 2022Microbiology

Multi-site phosphorylation of yeast Mif2/CENP-C promotes inner kinetochore assembly

S. M. Hinshaw, Y. Quan, J. Cai, A. Zhou, H. Zhou

The paper identifies multi-site phosphorylation of Mif2/CENP-C as essential for inner kinetochore assembly and accurate chromosome segregation in yeast.

bioRxiv · Nov 4, 2021Cell Biology

The structural basis for Ulp2 recruitment to the kinetochore

Y. Quan, S. M. Hinshaw, P.-C. Wang, S. C. Harrison, H. Zhou

This study identifies a mechanism for regulated kinetochore sumoylation by showing that Ulp2 recruitment to Ctf3/CENP-I controls sumoylation levels and chromosome segregation.

bioRxiv · Dec 30, 2020Cell Biology

Aging immune system-related blood cell DNA methylation can predict the onset of early stage colorectal cancer

Y. Quan, F. Liang, D. Wu, X. Yao, Y. Zhu, Y. Chen, A. Wu, D. Tang, B. Huang, R. Xu, Z. Lyu, Q. Yan, Z. Ning, Y. Li, J. Xiong

This study identifies DNA methylation of DZIP3 as a marker for early stage colorectal cancer, linked to aging and immune cell composition.

bioRxiv · Jan 13, 2020 · PreprintCancer Biology

Dissecting the dilemma between in vitro and in vivo drug screening: treating HepG2 cells with Artesunate as a model

K. U. Wong, S. L. Shi, H. Wang, F. Xing, Y. Quan, M. Zhao, L. Zhang, K. H. Wong, A. H. Wong, C. Deng

This study compares in vitro and in vivo drug responses to Artesunate in HepG2 cells, finding discrepancies in efficacy and biomarker expression.

bioRxiv · Aug 27, 2019 · PreprintCell Biology