Author

K. H. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 3 Organism:Arabidopsis· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. C. Colabardini· 2 shared F. Wang· 2 shared G. H. Goldman· 2 shared T. F. dos Reis· 2 shared A. Brown· 1 shared A. H. Wong· 1 shared A. Rokas· 1 shared A. S. Huffmyer· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. C. Colabardini

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metabolic dynamics of the coral-algal symbiosis from fertilization to settlement identify critical coral energetic vulnerabilities

A. S. Huffmyer, K. H. Wong, D. M. Becker, E. Strand, T. Mass, H. M. Putnam

The paper examines metabolic changes in coral-algal symbiosis from fertilization to settlement, identifying metamorphosis and settlement as critical energetic vulnerabilities to climate change.

bioRxiv · Mar 20, 2023Physiology

Temporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and drug resistance

M. N. Rai, C. Parsania, R. Rai, N. Shirgaonkar, K. Tan, K. H. Wong

The paper maps transcriptional responses of Candida glabrata during macrophage infection and identifies CgXbp1 as a key regulator of virulence and drug resistance.

bioRxiv · Sep 28, 2021Microbiology

Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin

A. C. Colabardini, F. Wang, Z. Dong, L. Pardeshi, M. C. Rocha, J. H. Costa, T. F. dos Reis, A. Brown, Q. Z. Jaber, M. Fridman, T. Fill, A. Rokas, I. Malavazi, K. H. Wong, G. H. Goldman

This study investigates transcriptional heterogeneity in Aspergillus fumigatus strains responding to caspofungin, identifying a core response and variable response linked to secondary metabolite biosynthesis and iron homeostasis.

bioRxiv · Jul 15, 2021Microbiology

Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals the potential mechanism of action of miltefosine

T. F. dos Reis, M. A. C. Horta, A. C. Colabardini, C. M. Fernandes, L. P. Silva, R. Bastos, M. V. L. Fonseca, F. Wang, C. Martins, M. Rodrigues, C. Silva Pereira, M. Del Poeta, K. H. Wong, G. H. Goldman

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

bioRxiv · May 19, 2021Microbiology

Dissecting the dilemma between in vitro and in vivo drug screening: treating HepG2 cells with Artesunate as a model

K. U. Wong, S. L. Shi, H. Wang, F. Xing, Y. Quan, M. Zhao, L. Zhang, K. H. Wong, A. H. Wong, C. Deng

This study compares in vitro and in vivo drug responses to Artesunate in HepG2 cells, finding discrepancies in efficacy and biomarker expression.

bioRxiv · Aug 27, 2019 · PreprintCell Biology