YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer
L. Cai, C. Xu, Y.-H. Tsai, P. Galbo, W. Gong, A. Storey, Y. Xu, S. Byrum, Y. Whang, J. Parker, S. Mackintosh, R. Edmondson, A. Tackett, J. Huang, D. Zheng, , G. G. Wang
This study identifies a YY1:BRD4-PFKP regulatory axis critical for castration-resistant prostate cancer tumorigenesis through cistrome analysis and functional experiments.
bioRxiv · Sep 17, 2020 · PreprintCancer Biology