A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
H. Fan, Y. Guo, Y.-H. Tsai, A. Storey, A. Kim, W. Gong, R. Edmondson, S. Mackintosh, H. Li, S. Byrum, A. Tackett, L. Cai, G. G. Wang
This paper identifies a conserved BAH module in BAHD1 that reads H3K27me3 and mediates gene silencing by recruiting histone deacetylases, essential for development.
bioRxiv · Mar 11, 2021Biochemistry