Author

S. Mackintosh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Storey· 2 shared A. Tackett· 2 shared G. G. Wang· 2 shared L. Cai· 2 shared R. Edmondson· 2 shared S. Byrum· 2 shared W. Gong· 2 shared Y.-H. Tsai· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

A. Storey

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Author profile →

2 papers

Recent·Most cited

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

H. Fan, Y. Guo, Y.-H. Tsai, A. Storey, A. Kim, W. Gong, R. Edmondson, S. Mackintosh, H. Li, S. Byrum, A. Tackett, L. Cai, G. G. Wang

This paper identifies a conserved BAH module in BAHD1 that reads H3K27me3 and mediates gene silencing by recruiting histone deacetylases, essential for development.

bioRxiv · Mar 11, 2021Biochemistry

YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer

L. Cai, C. Xu, Y.-H. Tsai, P. Galbo, W. Gong, A. Storey, Y. Xu, S. Byrum, Y. Whang, J. Parker, S. Mackintosh, R. Edmondson, A. Tackett, J. Huang, D. Zheng, , G. G. Wang

This study identifies a YY1:BRD4-PFKP regulatory axis critical for castration-resistant prostate cancer tumorigenesis through cistrome analysis and functional experiments.

bioRxiv · Sep 17, 2020 · PreprintCancer Biology