Author

Yan Huang

Jiangnan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Microbiology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aisheng Mo· 1 shared Bin YuiD· 1 shared Binjie Guo· 1 shared Chenxia HaniD· 1 shared Dan Du· 1 shared Deming RaoiD· 1 shared Deniz Erezyilmaz· 1 shared FU Fei· 1 shared

Activity by Year

2015-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioengineering

Aisheng Mo

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Author profile →

5 papers

Recent·Most cited

Serine Stabilizes SLC7A11 and Enhances Cystine Influx to Protect Against Acute Pancreatitis

Yan Huang, FU Fei, Lingli Deng, Yiqin Wang, Jiawang Li, Jiaxian Zhang, Jinxi Yang, Yijing Long, Manjiangcuo Wang, Chenxia Han, Lihui Deng, Pengfei Li, H Chen, Jiyang Dong, Xianghui Fu, , Dan Du

This study shows serine stabilizes SLC7A11 and enhances cystine influx, reducing oxidative stress and pancreatic injury in acute pancreatitis.

bioRxiv · May 6, 2026 · PreprintPharmacology & Toxicology

Mapping AAV capsid sequences to functions through function-guided in silico evolution

Binjie Guo, Hanyu Zheng, Xurong Lin, Haohan Jiang, Aisheng Mo, Hongyan Wei, Ru Zhang, Yubin Yuan, Yile Wu, Hengguang Li, Yunshuo Zhang, Zhuoyuan Song, Xuebin Ni, Yan Huang, Bin Yu, , Xuhua Wang

The paper introduces ALICE, a platform that uses function-guided in silico evolution to design AAV capsids with tailored properties, demonstrating improved targeting and tropism in mice.

Cell Press Blue · May 1, 2026Peer-reviewedBioengineering

Ganoderma lucidum alleviates kidney aging by modulating gut microbiota

Xiaojing Liu, Jiamin Zhao, Jia Liu, Wei Deng, Luwen Yan, Yan Huang, Liao Zhang, Zhihong Liu, Ming Cui, Huiwen Xiao, Xingzhong Liu

This study shows that Ganoderma lucidum spore powder alleviates kidney aging in mice by modulating gut microbiota and promoting nicotinamide riboside production, which improves renal function through the gut-kidney axis.

Journal of Ethnopharmacology · Aug 5, 2025Peer-reviewedMicrobiology

Activation-induced cytidine deaminase-based in vivo continuous evolution system enables rapid protein engineering

Xinyu Zhang, Zhanzhi Liu, Ying Xu, Deming Rao, Xiaoqian Chen, Zhigang Li, Yan Huang, Jing Wu

This paper introduces PEACE, an in vivo continuous evolution system using AID-T7 PNAP to enable rapid protein engineering by coupling gene polymorphism with toxin-antitoxin growth control.

bioRxiv · Jan 17, 2023 · PreprintMolecular Biology

The genetics of resistance to Morinda fruit toxin during the postembryonic stages in Drosophila sechellia

Yan Huang, Deniz Erezyilmaz

This study identifies genetic loci responsible for resistance to Morinda fruit toxin in Drosophila sechellia hybrids, revealing both dominant and recessive loci contributing to toxin resistance.

bioRxiv · Jan 20, 2015Evolutionary Biology