Dayu Lin

This study shows that repeated pup exposure converts virgin male mice to a parental state via calcitonin receptor-expressing neurons in the medial preoptic area.

The paper investigates genetic and neuronal factors influencing aggression in mice, finding strong genetic control and a role for VMHvl neurons.

This study identifies a neural circuit involving PAEsr1 and VMHvlNpy2r cells that supports the regulation of maternal aggression through plasticity and oxytocin signaling.

The paper identifies a shared neural circuit in male mice that controls pup-directed behaviors, with sex differences in cell activity balance influencing infanticide and paternal care.

The paper identifies BNC2 neurons in the hypothalamus that acutely suppress food intake by inhibiting AGRP neurons and are regulated by leptin, sensory cues, and nutritional status.

The paper shows that repeated winning in male mice leads to three stages of plasticity in the VMHvl aggression circuit, enhancing generalized aggression.

The paper develops state-space models to analyze multi-fiber photometry data and links neural dynamics to social behaviors in mice.

The paper identifies a hypothalamic oxytocin circuit that mediates defeat-induced social avoidance learning in mice.

This study shows that endogenous 17β-estradiol enhances reward prediction errors in the nucleus accumbens by reducing dopamine reuptake, thereby influencing reinforcement learning.

The paper develops GRAB sensors for detecting neuropeptides with high specificity and sensitivity, enabling in vivo monitoring of their release and function.

The paper identifies two distinct amygdala cell populations in male mice with different roles in social behavior, showing that MeAFoxp2 cells are specialized for male conspecific cues and aggression, while MeADbx1 cells respond broadly to social cues.

The paper investigates neural dynamics in the limbic system of male mice during sexual and aggressive behaviors, identifying distinct network states associated with each behavior.

This paper develops improved GRABNE sensors to monitor norepinephrine release in vivo with high sensitivity and uses them to study NE dynamics in mice.

The paper identifies neural circuits in female mice that drive opposing pup-directed behaviors, showing reciprocal inhibition between BNSTprEsr1 and MPOAEsr1 neurons during reproductive state changes.

The paper develops a new oxytocin sensor to study compartmental OT release in neurons and finds distinct calcium channel roles and fusion machinery differences in axons and somatodendritic regions.

This study uses a genetically encoded dopamine sensor to measure dopamine release in the nucleus accumbens during social behaviors in mice, revealing distinct patterns in different phases of social interaction.

The paper develops and optimizes GRABDA fluorescent sensors to monitor dopaminergic activity with high sensitivity and resolution in vivo.

The paper shows that social interactions between mother mice and virgin mice activate oxytocin neurons, enabling the virgins to acquire maternal behavior through social transmission.

The paper identifies that lPAG neurons encode a simplified attack-selective signal during aggression, with specific spiking patterns and projections from VMHvl neurons.

The paper develops GRABNE sensors for rapid, specific in vivo detection of norepinephrine, demonstrating their use in various experimental contexts.

This paper develops GRABDA sensors to measure dopamine with high precision in multiple organisms during complex behaviors.

The paper shows that PVN CRF neurons respond rapidly to aversive and appetitive stimuli in mice, suggesting their role in sensory detection and neuroendocrine regulation.