Author

Yongzhi Chen

University of Massachusetts Chan Medical SchoolPrimary ORCID profile (0000-0003-0458-4368 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Yongzhi CheniD1 paper · Genapsys (United States)

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Katherine A. FitzgeraldiD· 2 shared Andrew J. OliveiD· 1 shared Anthony M. Coon· 1 shared Christopher M. SassettiiD· 1 shared David M. Knipe· 1 shared Jafira M. Johnson· 1 shared Jennifer Bernier· 1 shared Joanne Michelle KahlenbergiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Katherine A. FitzgeraldORCID

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2 papers

Recent·Most cited

IFN-κ directs antiviral immunity in human skin

Jafira M. Johnson, Laurellee Payne, Pooja Parameswaran, Yongzhi Chen, Mrinal K. Sarkar, Anthony M. Coon, Joanne Michelle Kahlenberg, Johann Eli Gudjonsson, Katherine A. Fitzgerald, Mehdi Rashighi, Megan H. Orzalli

This study shows that keratinocytes produce IFN-kappa constitutively to protect human skin against RNA and DNA viruses through distinct antiviral mechanisms.

bioRxiv · Sep 23, 2026 · PreprintImmunology

CNBP controls c-Rel dependent IL-12 β gene transcription and Th1 immunity

Yongzhi Chen, Shruti Sharma, Patricia A. Assis, Zhaozhao Jiang, Andrew J. Olive, Saiyu Hang, Jennifer Bernier, Jun R. Huh, Christopher M. Sassetti, David M. Knipe, Riccardo T. Gazzinelli, Katherine A. Fitzgerald

This study identifies CNBP as a regulator of c-Rel dependent IL-12β gene transcription and Th1 immunity, showing its role in macrophage function and resistance to toxoplasmosis.

bioRxiv · Feb 1, 2018 · PreprintImmunology