Author

Young Jae Lee

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Balaji KrishnamacharyiD· 1 shared Benjamin LiechtyiD· 1 shared Daphne Zhu· 1 shared H LI· 1 shared Hao CheniD· 1 shared Jingjie ZhuiD· 1 shared Jorge J. PalopiD· 1 shared Junfang WuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Balaji KrishnamacharyORCID

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1 paper

Recent·Most cited

cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy

Yige Huang, Li Fan, Man Ying Wong, Zhuofan Lei, Balaji Krishnamachary, Daphne Zhu, Mika P. Cadiz, Ravi Kumar Nagiri, Pearly Ye, Kendra Norman, Maitreyee Bhagwat, Young Jae Lee, H LI, Jingjie Zhu, Sadaf Amin, , Li Gan

This study identifies cGAS-mediated IFN-I signaling as a driver of disease progression in drug-refractory epilepsy, showing that targeting cGAS reduces epileptic phenotypes and inflammation.

bioRxiv · Feb 2, 2026 · PreprintNeuroscience