Author

Maitreyee Bhagwat

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2

Frequent Co-Authors

Jingjie ZhuiD· 4 shared Kendra Norman· 4 shared Li FaniD· 4 shared Man Ying WongiD· 4 shared Pearly Ye· 4 shared Daphne Zhu· 3 shared Shiaoching GongiD· 3 shared Subhash C. SinhaiD· 3 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Jingjie ZhuORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity

Caitlin Castagnola, Roberta Marongiu, Yuansong Wan, Eileen Ruth Torres, Li Fan, Minwoo Wendy Jang, Qiaoling Cui, Jihye Kim, Pearly Ye, Jingjie Zhu, Alisa Panichkina, Alexandra B. Fall, Kendra Norman, Beichen Gao, Nessa R. Foxe, , Li Gan

The paper identifies a microglial gene program linked to dyskinesia in Parkinson's disease and shows that sTREM2 reduces dyskinesia by modulating TrkB signaling and synaptic plasticity.

bioRxiv · May 7, 2026 · PreprintNeuroscience

cGAS inhibition delays TDP-43-driven ALS Pathogenesis

Yajing Liu, Weixi Feng, Abulimiti Aikedan, Se-In Lee, Maitreyee Bhagwat, Ravi Kumar Nagiri, Man Ying Wong, Sadaf Amin, Wenhui Qu, Jingjie Zhu, Si-Yu Wang, Pearly Ye, Kendra Norman, Guillermo Coronas‐Samano, Marta Olah, , Li Gan

This study identifies cGAS as a key mediator of TDP-43 pathology in ALS and shows that its inhibition reduces RNA splicing defects and neurodegeneration.

bioRxiv · Feb 26, 2026 · PreprintNeuroscience

cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy

Yige Huang, Li Fan, Man Ying Wong, Zhuofan Lei, Balaji Krishnamachary, Daphne Zhu, Mika P. Cadiz, Ravi Kumar Nagiri, Pearly Ye, Kendra Norman, Maitreyee Bhagwat, Young Jae Lee, H LI, Jingjie Zhu, Sadaf Amin, , Li Gan

This study identifies cGAS-mediated IFN-I signaling as a driver of disease progression in drug-refractory epilepsy, showing that targeting cGAS reduces epileptic phenotypes and inflammation.

bioRxiv · Feb 2, 2026 · PreprintNeuroscience

APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition

Sarah A. Naguib, Chloe Lopez-Lee, Eileen Ruth S. Torres, Se-In Lee, Jingjie Zhu, Daphne Zhu, Pearly Ye, Kendra Norman, Mingrui Zhao, Man Ying Wong, Yohannes A. Ambaw, Rodrigo Castaneda, Wei Wang, Tark Patel, Maitreyee Bhagwat, , Li Gan

The R136S mutation on APOE3 enhances resistance to tau-related pathology and toxicity by downregulating the cGAS-STING-IFN signaling pathway.

bioRxiv · Apr 25, 2024 · PreprintNeuroscience

MARK1 regulates dendritic spine morphogenesis and cognitive functions in vivo

Emily C. Kelly-Castro, Rebecca Shear, Ankitha H. Dindigal, Maitreyee Bhagwat, Huaye Zhang

This study shows that MARK1 is essential for dendritic spine morphogenesis and cognitive functions in vivo, as evidenced by spine defects and behavioral impairments in Mark1 knockout mice.

Experimental Neurology · Mar 12, 2024Peer-reviewedNeuroscience