Author

Yves Cambet

University of Geneva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:electronic health records· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Antonio GrondiniD· 1 shared Arnaud GaudryiD· 1 shared Bita Asghariastanehei· 1 shared Bohumil MacoiD· 1 shared Caroline TappareliD· 1 shared Cyril Castelbou· 1 shared Élie NaderiD· 1 shared Élodie Alessandri-GradtiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Antonio GrondinORCID

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2 papers

Recent·Most cited

Otenabant is a Selective Antagonist of Human PIEZO1

Vincent Jaquet, Reeta Penttinen, Gorane Rodríguez-Urquirizar, Cyril Castelbou, Yves Cambet, Nicolas Rosa, Mathilde Bourdin, Bita Asghariastanehei, Franciele de Lima, Marie Martin, Élie Nader, Selma Angèlica Serra, José M. Fernández‐Fernández, Nicoletta Murciano, Philippe Connes, , Nicolas Demaurex

The paper identifies Otenabant, a CB1 antagonist, as a potent and selective PIEZO1 inhibitor through high-throughput screening and validates its effects across multiple assays.

bioRxiv · Apr 30, 2026 · PreprintPharmacology & Toxicology

Human airway organoids as a high-throughput screening platform for antiviral natural products discovery

Mathieu Hubert, Paola Haemmerli, Laurence Marcourt, Emy Lara-Quintero, Loan Arthaud, Luis-Manuel Quirós-Guerrero, Sarah Donnaray, Katia Rimensberger, Arnaud Gaudry, Élodie Alessandri-Gradt, Georgios Stroulios, Yves Cambet, François Prodon, Bohumil Maco, Samuel Constant, , Caroline Tapparel

This study uses human airway organoids to screen 764 natural plant extracts for antiviral activity against RSV, identifying 45 active compounds with distinct mechanisms.

bioRxiv · Feb 4, 2026 · PreprintMicrobiology