Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
X. Tian, C. Li, A. Huang…·T. Ying
This study shows that the SARS-CoV-specific antibody CR3022 binds strongly to 2019-nCoV RBD with a KD of 6.3 nM, while other antibodies targeting the ACE2 site fail to bind, highlighting the importance of RBD differences for cross-reactivity.