Author

Z.-Y. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Armstrong· 1 shared A. P. Rameshbabu· 1 shared B.-B. Sun· 1 shared C. Zhang· 1 shared F. Liang· 1 shared G.-B. Zhou· 1 shared G.-Z. Wang· 1 shared H. Yu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

A. M. Armstrong

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Author profile →

2 papers

Recent·Most cited

Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation

W. Zhu, W. Du, A. P. Rameshbabu, A. M. Armstrong, S. Silver, Y. Kim, W. Wei, Y. Shu, X. Liu, M. A. Lewis, K. P. Steel, Z.-Y. Chen

This study uses genome editing in adult mice with a MIR96 mutation to restore hearing, showing efficacy that improves with earlier intervention.

bioRxiv · Oct 26, 2023 · PreprintBioengineering

Degradation of SARS-CoV-2 receptor ACE2 by tobacco carcinogen-induced Skp2 in lung epithelial cells

G.-B. Zhou, G.-Z. Wang, Q. Zhao, F. Liang, C. Zhang, H. Zhang, J. Wang, Z.-Y. Chen, R. Wu, H. Yu, B.-B. Sun, R. Feng, K.-F. Xu

The paper shows tobacco carcinogens increase ACE2 mRNA but reduce ACE2 protein levels via Skp2-mediated ubiquitination, decreasing SARS-CoV-2 infection in lung cells.

bioRxiv · Oct 13, 2020Cell Biology