Author

Zeren Toksoy

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Fadi G. AkariD· 2 shared Lawrence H. YoungiD· 2 shared Marine Cacheux· 2 shared Xiaohong WuiD· 2 shared Anton Seyfried· 1 shared Gerald I. ShulmaniD· 1 shared Jonathan M. GrangeriD· 1 shared Leigh GoedekeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

Fadi G. AkarORCID

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2 papers

Recent·Most cited

Transient AMPK activation by nutrient stress of high fat diet preserves cardiac electrophysiological stability and protects against arrhythmias

Michael W. Rudokas, Margaret McKay, Xiaohong Wu, Jonathan M. Granger, Yancey D. Williams, Markus Bögner, Taekyung Kang, Anton Seyfried, Zeren Toksoy, Marine Cacheux, Lawrence H. Young, Fadi G. Akar

This study shows that AMPK activation by high-fat diet reduces arrhythmia risk by improving cardiac electrophysiology and mitochondrial function.

bioRxiv · Jun 11, 2025 · PreprintPhysiology

Role of AMPK in Atrial Metabolic Homeostasis and Substrate Preference

Zeren Toksoy, Yina Ma, Leigh Goedeke, Wenxue Li, Xiaoyue Hu, Xiaohong Wu, Marine Cacheux, Yansheng Liu, Fadi G. Akar, Gerald I. Shulman, Lawrence H. Young

This study shows that atrial AMPK deletion shifts metabolism from fatty acid oxidation to pyruvate oxidation and disrupts metabolic pathways, contributing to atrial remodeling and arrhythmia.

bioRxiv · Aug 29, 2024 · PreprintPhysiology