Author

Ziya L. Gokaslan

Brown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alfredo Quinones Hinojosa· 1 shared Clark C. CheniD· 1 shared Claudia PalenaiD· 1 shared Efrosini KokkoliiD· 1 shared Eric Wong· 1 shared Gatikrushna SinghiD· 1 shared Iteeshree MohapatraiD· 1 shared Johnny C. Akers· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alfredo Quinones Hinojosa

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2 papers

Recent·Most cited

Modulating populational variance of methyl-guanine methyl transferase expression through miR-181d degradation: a novel mechanism of temozolomide resistance

Gatikrushna Singh, Shilpi Singh, Iteeshree Mohapatra, Stefan Kim, Mayur Sharma, Johnny C. Akers, Thien Phuc Nguyen, Eric Wong, Margot Martinez-Moreno, Efrosini Kokkoli, Shobha Vasudevan, Sean Edward Lawler, Wafik S. El‐Deiry, Ziya L. Gokaslan, Clark C. Chen

The paper shows that miR-181d degradation via a PNPT1-ATR feed-forward loop increases MGMT expression variance, leading to temozolomide resistance in glioblastoma cells.

bioRxiv · Apr 22, 2025 · PreprintCancer Biology

Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage Response

Oluwaseun Oluwadara Akinduro, Paola Suarez Meade, Paula V. Schiapparelli, Rachel Whitehead, Stephany Yi Tzeng, Steven S. Rosenfeld, Sungjune Kim, Claudia Palena, Ziya L. Gokaslan, Jordan J. Green, Alfredo Quinones Hinojosa

This study shows that YAP inhibition with verteporfin increases radiosensitivity in chordoma by blocking DNA repair and causing G2M arrest.

bioRxiv · Nov 3, 2024 · PreprintCancer Biology