Author

Erik B. Bloss

Jackson LaboratoryORCID 0000-0001-5031-4591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Justice Pomeroy-Tuck· 3 shared Kourtney C. GrahamiD· 3 shared Emily W. NickersoniD· 2 shared Gareth R. HowelliD· 2 shared Sarah E. HeueriD· 2 shared Adrian L. OblakiD· 1 shared Amanda A. HewesiD· 1 shared Anna L Drillen· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Justice Pomeroy-Tuck

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Conserved synaptic modifications by humanized tau through diverse isoform- and mutation-specific intracellular interactions

Emily Nickerson, Justice Pomeroy-Tuck, Samia Pratt, Carly Rodriguez, Tengteng Zhao, Tim Stodola, Brian Hoffman, Rick Maser, Erik Bloss

The paper investigates how different humanized tau isoforms and mutations affect synaptic connectivity and interact with mitochondrial proteins in cortical neurons.

bioRxiv · Nov 4, 2026 · PreprintNeuroscience

Characterization of the knock-in AppSAA mouse model as a powerful tool for Alzheimer's disease preclinical research.

Lucy J. Sloan, Dylan T. Garceau, Nick Ryan, Justice Pomeroy-Tuck, Ritesh Chidambaram, Tim Ragan, Ravi S. Pandey, Erik B. Bloss, Gregory W. Carter, Adrian L. Oblak, Michael Sasner

The paper characterizes the AppSAA knock-in mouse model, showing it recapitulates age-dependent Alzheimer's disease phenotypes and provides a tool for preclinical research.

bioRxiv · Sep 10, 2026 · PreprintNeuroscience

Sex-specific plasticity mechanisms mediating fear extinction

Kourtney C. Graham, Justice Pomeroy-Tuck, Grace K O'Brien, Lacey K Webber, Anna L Drillen, Luke T. Coddington, Xinyu Zhao, Erik B. Bloss

The paper shows that male and female mice use different synaptic plasticity mechanisms for fear extinction, with males showing structural remodeling and GRIN2B dependence, while females do not.

bioRxiv · May 19, 2026 · PreprintNeuroscience

Genetic context drives age-related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits

Sarah E. Heuer, Emily W. Nickerson, Gareth R. Howell, Erik B. Bloss

The paper investigates age-related synaptic changes in two mouse strains, finding differential synaptic loss and efficiency in specific circuits, suggesting genetic factors influence cognitive decline resistance.

Aging Cell · Dec 21, 2023Peer-reviewedNeuroscience

Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimers disease

Sarah E. Heuer, Kelly J. Keezer, Amanda A. Hewes, Kristen D. Onos, Kourtney C. Graham, Gareth R. Howell, Erik B. Bloss

The paper shows genetic context influences microglia-synaptic interactions in AD mouse models, with differential effects in B6 and PWK strains.

bioRxiv · Apr 28, 2023 · PreprintNeuroscience

Hippocampal and thalamic afferents form distinct synaptic microcircuits in the mouse frontal cortex

Kourtney C. Graham, Nelson Spruston, Erik B. Bloss

The paper identifies distinct synaptic microcircuits in the mouse frontal cortex, showing hippocampal and thalamic afferents target different inhibitory and excitatory neuron classes.

bioRxiv · Mar 12, 2021 · PreprintNeuroscience