Ivan Gerling

This study identifies transcriptional impairments in mitochondrial and protein homeostasis pathways in islets during type 1 diabetes pathogenesis, independent of T-cell infiltration.

This study shows that beta cell dysfunction occurs in type 1 diabetes independently of T cell infiltration, using human pancreas tissue slices from recently diagnosed patients.

This study shows chronic ER stress induces β-cell plasticity, but excessive stress leads to identity loss and is linked to T1D progression.