Author

Luciano da Fontoura Costa

Universidade de São PauloORCID 0000-0001-5203-4366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandre Savard· 1 shared Baptiste LacosteiD· 1 shared Cesar Henrique CominiD· 1 shared Gareth M. RurakiD· 1 shared Gianfilippo CoppolaiD· 1 shared Joanna Raman‐Nair· 1 shared Julie Ouellette· 1 shared Karan ThakuriD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandre Savard

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Author profile →

3 papers

Recent·Most cited

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.

Moises Freitas Andrade, Cesar Henrique Comin, Peter C. Van Dyken, Julie Ouellette, Joanna Raman‐Nair, Nicole Blakeley, Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micaël Carrier, Karan Thakur, Alexandre Savard, Gareth M. Rurak, Marie‐Ève Tremblay, , Baptiste Lacoste

This study identifies Hmgb1 in astrocytes as critical for postnatal astrocyte morphogenesis and cerebrovascular maturation, affecting endothelial ultrastructure and neurovascular coupling in adult mice.

bioRxiv · Apr 29, 2023 · PreprintDevelopmental Biology

Revisiting Colocalization from the Perspective of Similarity

Luciano da Fontoura Costa

The paper explores the use of multiset similarity indices to quantify colocalization between concentrations, suggesting they can provide complementary information to Pearson correlation.

bioRxiv · May 23, 2022 · PreprintSystems Biology

Accelerated Simulation of Large Reaction Systems Using a Constraint-Based Algorithm

Paulo E. P. Burke, Luciano da Fontoura Costa

This paper introduces a constraint-based algorithm for simulating large reaction systems, showing it outperforms existing methods in computational efficiency for high molecule and reaction channel counts.

bioRxiv · Oct 31, 2020 · PreprintSystems Biology