Shungo Adachi

This study introduces TISCA2 and IncepTIS to map and predict stress-responsive translation initiation sites, revealing tissue-specific patterns and enabling engineered mRNA 5' leaders.

This paper introduces RLMHelix, an alignment-free method to discover conserved RNA structures in the human genome, identifying new candidates that correlate with RNA-binding protein interactions.

The paper develops an EASY-HSV system using HSV-1 genome-maintaining HEK293 cells to simplify and increase the yield of HSV amplicon vector production.

The paper identifies phosphorylation events and thermosensing mechanisms that regulate CLK1 localization to nuclear stress bodies during thermal stress recovery.

This paper introduces SCALE-CLIP, a method to generate comparable RBP binding maps, and defines a positional and combinatorial regulatory code for alternative splicing.

This study identifies cytoplasmic roles of HSATIII RNAs in forming RNA granules and producing proteins during thermal stress recovery.

This study examines the transcriptomic and proteomic responses of Pyrococcus furiosus to acute heat shock, revealing proteome stability, translation suppression, and a potential role for a histone-like protein in chromatin formation.

This study characterizes the RNA-guided nuclease-protease complex Cas7-11-Csx29, showing target RNA binding activates Csx29 to cleave Csx30, leading to cell death.

The paper shows that lncRNA-dependent nuclear stress bodies promote intron retention via SR protein phosphorylation during thermal stress recovery.

The paper identifies Nxf2 as a key component in the Piwi-piRNA pathway, showing it forms complexes that stabilize Piwi and Panx and initiate co-transcriptional silencing of target transcripts.

The paper shows that codon bias affects mRNA stability in humans through ILF2, with GC3 codons stabilizing and AT3 codons destabilizing mRNA.