Tanveer Singh Batth

KRysin, a bispecific protease, improves plasma and phosphoproteomics by enhancing digestion completeness and PTM coverage compared to trypsin.

This study maps the human sperm proteome across compartments, donors, and individual cells, revealing conserved and variable proteins and linking mitochondrial dysfunction to male infertility.

This paper introduces Arg-C Zero, a high-fidelity protease with near-zero missed cleavages, demonstrating its utility in proteomics, especially for analyzing post-translational modifications.

This study compares three LysC homologues for proteomics, finding A. lyticus LysC provides better peptide identification and digestion efficiency than others.

The paper develops a proteomics method to identify drug targets across the proteome, revealing organ-specific interactions and global drug effects.

The paper identifies an N-terminal histidine methyltransferase (NHMT) responsible for methylation of LPMOs in filamentous fungi, showing its role in protecting LPMOs from auto-oxidative inactivation.